SMART: Pfam domain DLIC

The domain within your query sequence starts at position 2 and ends at position 179; the E-value for the DLIC domain shown below is 3.3e-8.

PSETLWEIAKAEVEKRRSHGSEGDGAEIGEKSVFFIGSKNGGKTTIILRCLDRDESAKPT
LALEYTYGRKTKGHNTPKDIAHFWELGGGTSLLDLISIPITVDTLRTFSIVLVLDLSKPN
DLWSTMENLLQATKSHVDKVIMKLGKTSSKASAEMRQRMWSVVQKDHPDRELIDPFPI

DLIC

PFAM accession number:	PF05783
Interpro abstract (IPR022780):	This entry consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species. DLIC1 is known to be involved in assembly, organisation, and function of centrosomes and mitotic spindles when bound to pericentrin [ (PUBMED:10545494) (PUBMED:10893222) ]. DLIC2 is a subunit of cytoplasmic dynein 2 that may play a role in maintaining Golgi organisation by binding cytoplasmic dynein 2 to its Golgi-associated cargo [ (PUBMED:11907264) ].

PFAM accession number:

PF05783

Interpro abstract (IPR022780):

This entry consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species. DLIC1 is known to be involved in assembly, organisation, and function of centrosomes and mitotic spindles when bound to pericentrin [ (PUBMED:10545494) (PUBMED:10893222) ]. DLIC2 is a subunit of cytoplasmic dynein 2 that may play a role in maintaining Golgi organisation by binding cytoplasmic dynein 2 to its Golgi-associated cargo [ (PUBMED:11907264) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DLIC