The domain within your query sequence starts at position 24 and ends at position 235; the E-value for the DOR domain shown below is 4.8e-84.



PFAM accession number:PF14839
Interpro abstract (IPR029431):

This entry represents tumour protein p53-inducible nuclear protein 1 and 2 (Tp53inp1 and Tp53inp2). There is only DOR/Tp53inp2 in invertebrates, while both Tp53inp1 and Tp53inp2 can be found in vertebrates. The vertebrates Tp53inp1 gene may have arisen by gene duplication [ (PUBMED:22470510) ].

Tumour protein p53-inducible nuclear protein 1 is an antiproliferative and proapoptotic protein involved in cell stress response. It acts as a dual regulator of transcription and autophagy [ (PUBMED:11511362) ].

DOR/TP53INP2 is a bifunctional protein that functions as a modulator of autophagy and in gene transcription [ (PUBMED:22470510) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DOR