The domain within your query sequence starts at position 452 and ends at position 617; the E-value for the DUF1295 domain shown below is 1.1e-9.

LLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVI
FRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSL
PCGFNHLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRV

DUF1295

DUF1295
PFAM accession number:PF06966
Interpro abstract (IPR010721):

This family contains a number of bacterial and eukaryotic proteins of unknown function that are approximately 300 residues long.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF1295