The domain within your query sequence starts at position 17 and ends at position 319; the E-value for the DUF1394 domain shown below is 2.1e-150.

HFFLDFENAQPTEGEREIWNQISAVLQDSESILTDLQAYKGAGPEIRDAIQNPNDIQLQE
KAWNAVCPLVVRLKRFYEFSIRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILH
FTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPM
LKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLETPEYRSRFTSEETLMFCMRVM
VGVIILYDHVHPVGAFCKTSKIDMKGCIKVLKEQAPDSVEGLLNALRFTTKHLNDESTSK
QIR

DUF1394

 DUF1394
PFAM accession number:PF07159
Interpro abstract (IPR009828):

This domain has been annotated as Rac1-binding domain [ (PUBMED:31413787) (PUBMED:30250061) ]. It can be found in human CYRIA/CYRIB and at the N terminus of CYFIP1/2 [ (PUBMED:31285585) ]. CYFIP proteins are known RAC1 effectors that stimulate actin polymerization [ (PUBMED:31285585) ]. In mice, CYRIB (also known as CYRI or FAM49B) negatively regulates RAC1-driven cytoskeletal remodelling and plays a role in restricting infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes [ (PUBMED:31285585) ].

GO function:Rac GTPase binding (GO:0048365)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF1394