The domain within your query sequence starts at position 132 and ends at position 217; the E-value for the DUF3446 domain shown below is 1.4e-30.
GRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPTSSSSAPSPAASSSSSASQSPPLSCA VPSNDSSPIYSAAPTFPTPNTDIFPE
DUF3446 |
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| PFAM accession number: | PF11928 |
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| Interpro abstract (IPR021849): | Proteins containing this domain include early growth response protein 1/2/3 (EGR1/2/3). EGR1 is a transcriptional regulator that binds specifically to 9-bp target sequences containing two CpG sites that can potentially be methylated at four cytosine bases [ (PUBMED:25999311) ]. EGR2, also known as Krox20, is an E3 ligase that sumoylates its Nab coregulators [ (PUBMED:21836637) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF3446