The domain within your query sequence starts at position 14 and ends at position 259; the E-value for the DUF4498 domain shown below is 8.2e-114.

FRFLPHRTFSSLSAREITSRLRQWSMLGRIQAQAFSFDQTFQPYQKDDFVMAFFKDPNVI
PNLQLLSDSSGQWTTLGSEVKKIEAINVPCTQLSMSFFQRLYDENIVRESGHIVKCLDSF
CDPFLISDELRKVLLMEDSEKYEVFSPVEREEFLFCLFKHLCLGGSLCQYEDVLKPYLET
AKLIYKDLVSVRKHPRTKEIQITSSVFKVKAYDSVGVCYPSPKEHEQTFSYFVVDPIKRH
VNVLYH

DUF4498

 DUF4498
PFAM accession number:PF14926
Interpro abstract (IPR029416):

CFAP300 is a cilia- and flagella-associated protein that is essential for assembly of dynein arms. Mutations in the CFAP300 gene (C11orf70) cause defective cilia motility and primary ciliary dyskinesia [ (PUBMED:29727692) (PUBMED:29727693) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF4498