The domain within your query sequence starts at position 1 and ends at position 270; the E-value for the DUF4545 domain shown below is 7.3e-116.

MTEKILEKFDALEEKERILEAIRENNTDRHHRQRKKPLITPLLFDLHVQFGDTITPSASK
IIKNKPHDLKNPKRSVSFKYKPNNSRSDLEESDLRPPILGTMINYEESKLMDHKEENLKS
RPISLRYLKDKDETEYANPLPFPQLWSKHLCKKSAESSVPTPKLTNESNASKKENVSPPF
TDQHESRTKKSMHSTDHSADSSTSRGKCPPKGITKESELTRNDEARKPHPVKQSIMLPLD
CEDLLKNPKIKTIDLRPAVTVHTSMAVINN

DUF4545

DUF4545
PFAM accession number:PF15078
Interpro abstract (IPR027847):

This family of proteins is found in eukaryotes. The human member of this family is C1orf141.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DUF4545