The domain within your query sequence starts at position 10 and ends at position 286; the E-value for the DuoxA domain shown below is 5.5e-114.



PFAM accession number:PF10204
Interpro abstract (IPR018469):

DuoxA (Dual oxidase maturation factor) is the essential protein necessary for the final release of DUOX2 (an NADPH:O2 oxidoreductase flavoprotein) from the endoplasmic reticulum. Dual oxidases (DUOX1 and DUOX2) constitute the catalytic core of the hydrogen peroxide generator, which generates H2O2 at the apical membrane of thyroid follicular cells, essential for iodination of thyroglobulin by thyroid peroxidases. DuoxA carries five membrane-integral regions including a reverse signal-anchor with external N terminus (type III) and two N-glycosylation sites [ (PUBMED:16651268) ]. It is conserved from nematodes to humans.

GO process:protein transport (GO:0015031)
GO component:endoplasmic reticulum membrane (GO:0005789), integral component of membrane (GO:0016021)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry DuoxA