The domain within your query sequence starts at position 44 and ends at position 266; the E-value for the ECSIT domain shown below is 6.2e-108.
SAATHKDEPWLVPRPPEPQRKPIKVPAMHEDSFKPSGNRERDKASFLNAVRSFGAHNVRK RGHVDFIYLALRKMPEFGVERDLSVYNLLLDVFPKEVFRPRNVIQRIFVHYPRQQECGVA VLEQMERHGVMPSAETEFLLIQIFGRKSYPMLKFLRMKLWFTRFKNINPYPVPRDLPQDP LDLAKLGLRHMEPDLSAKVTVYQMSLPSDSTGMEDPTQPHIVG
ECSIT |
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PFAM accession number: | PF06239 |
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Interpro abstract (IPR010418): | Activation of NF-kappaB as a consequence of signalling through the Toll and IL-1 receptors is a major element of innate immune responses. ECSIT plays an important role in signalling to NF-kappaB, functioning as the intermediate in the signalling pathways between TRAF-6 and MEKK-1 [ (PUBMED:10465784) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry ECSIT