The domain within your query sequence starts at position 43 and ends at position 152; the E-value for the EpoR_lig-bind domain shown below is 3.6e-12.
LGTSSSGKPRFTKCRSPELETFSCYWTEGDNPDLKTPGSIQLYYAKRESQRQAARIAHEW TQEWKECPDYVSAGKNSCYFNSSYTSIWIPYCIKLTTNGDLLDQKCFTVD
EpoR_lig-bind |
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PFAM accession number: | PF09067 |
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Interpro abstract (IPR015152): | Members of this entry include the growth hormone and erythropoietin receptors. The latter interacts with erythropoietin (EPO), with subsequent initiation of the downstream chain of events associated with binding of EPO to the receptor, including EPO-induced erythroblast proliferation and differentiation through induction of the JAK2/STAT5 signalling cascade. The domain adopts a secondary structure composed of a short amino-terminal helix, followed by two beta-sandwich regions [ (PUBMED:9774108) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry EpoR_lig-bind