The domain within your query sequence starts at position 344 and ends at position 566; the E-value for the Folliculin_C domain shown below is 8.4e-94.

TGFKSLRHMRQVLGAPSFRMLAWHVLMGNQVIWKSRDVNLVHSAFEVLRTMLPVGCVRII
PYSSQYEEAYRCNFLGLSPPVPIPAHVLASEFVVVVEVHTATRSNLHPAGCEDDQSLSKY
EFVVTSGSPVAADRVGPTILNKIEAALTNQNLSVDVVDQCLICLKEEWMNKVKVLFKFTK
VDSRPKEDTQKLLSVLGASEEDNVKLLKFWMTGLSKTYKSHLM

Folliculin_C

 Folliculin_C
PFAM accession number:PF16692
Interpro abstract (IPR032035):

This is the C-terminal domain of folliculin. This domain shares structural similarity with DENN domain of DENN1B (a Rab GEF), and has guanine nucleotide exchange factor (GEF) activity [ (PUBMED:22977732) ].

GO function:guanyl-nucleotide exchange factor activity (GO:0005085)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Folliculin_C