SMART: Pfam domain GED

The domain within your query sequence starts at position 1 and ends at position 43; the E-value for the GED domain shown below is 3.3e-7.

XNLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDI

GED

PFAM accession number:	PF02212
Interpro abstract (IPR003130):	Dynamin GTPase effector domain found in proteins related to dynamin. Dynamin is a GTP-hydrolysing protein that is an essential participant in clathrin-mediated endocytosis by cells. It self-assembles into 'collars' in vivo at the necks of invaginated coated pits; the self-assembly of dynamin being coordinated by the GTPase domain. Mutation studies indicate that dynamin functions as a molecular regulator of receptor-mediated endocytosis [ (PUBMED:10206643) ].
GO function:	GTPase activity (GO:0003924), GTP binding (GO:0005525)

PFAM accession number:

PF02212

Interpro abstract (IPR003130):

Dynamin GTPase effector domain found in proteins related to dynamin.

Dynamin is a GTP-hydrolysing protein that is an essential participant in clathrin-mediated endocytosis by cells. It self-assembles into 'collars' in vivo at the necks of invaginated coated pits; the self-assembly of dynamin being coordinated by the GTPase domain. Mutation studies indicate that dynamin functions as a molecular regulator of receptor-mediated endocytosis [ (PUBMED:10206643) ].

GO function:

GTPase activity (GO:0003924), GTP binding (GO:0005525)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry GED