The domain within your query sequence starts at position 649 and ends at position 1000; the E-value for the HPS3_C domain shown below is 1.8e-175.

MKNIDPLTALHYLRKLDSCGVSPVLVTLTKAAVALKMGDLDMYRNEMKSHSEMKLVYGFI
LEPRLLIQQWKGQIVPTELAIDLKETQPGLLVASVLGLQKNDKIGIVETDSFFKVLCGKD
EDAVPQLLIDFWEAQLVACLPNVVLEELFFKLISQYVWRLSERRCPDTVPLRTAEDLINA
CSHYGLVNPWVHVLTTSDSLADKNYTDDLLKLQSLICSPSLDVASIIPFLEPLSEDTVAG
LSTHALCHTRLQEYEQCIDTLLERCPEAVIAYANQELKEDHWILWWKKLLPELCQRVKSG
GERSHLHLSLLKETLSVIAVGLDLRDFLNVLPEDGAAAFFLPYLLFCSRKKS

HPS3_C

HPS3_C
PFAM accession number:PF14763
Interpro abstract (IPR029438):

This entry represents the C-terminal domain of the Hermansky-Pudlak syndrome 3 (HPS3) protein. In human HPS3, this region carries a number of tyrosine sorting motifs and the second of two di-leucine sorting boxes at residues 711-717, as well as the ER membrane-retention signal KKPL at residues 1000-1003. Hermansky-Pudlak syndrome caused by mutations in HPS3 gene is a genetically heterogeneous autosomal recessive disorder characterised by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects [ (PUBMED:11455388) (PUBMED:11590544) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry HPS3_C