The domain within your query sequence starts at position 70 and ends at position 297; the E-value for the HlyIII domain shown below is 1.7e-47.
FQKHNEVVNVWTHLLAALAVLLRFWAFVEAGALQWASPHTLPLLLFILSSITYLTCSLLA HLLQSKSELSHYTFYFVDYVGVSVYQYGSALAHFFYSSDQAWYELFWIFFLPAAAFCGWL SCAGCCYAKYRYRRPYPVMRKICQVVPAGLAFVLDISPVAHRVALCHLAGCQEQAAWYHT LQILFFLVSAYFFSCPVPEKYFPGSCDIVGHGHQIFHAFLSVCTLSQL
HlyIII |
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PFAM accession number: | PF03006 |
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Interpro abstract (IPR004254): | Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus [ (PUBMED:7495855) ]. YOL002c (AdipoR-like receptor IZH2) from Saccharomyces cerevisiae encodes a protein that plays a key role in metabolic pathways that regulate lipid and phosphate metabolism [ (PUBMED:11916977) (PUBMED:15664187) ]. In eukaryotes, members are seven-transmembrane pass molecules found to encode functional receptors with a broad range of apparent ligand specificities, including progestin and adiponectin (AdipoQ) receptors (AdipoR), and hence have been named PAQR proteins [ (PUBMED:16044242) ]. The mammalian members include progesterone binding proteins [ (PUBMED:17082257) ]. Unlike the case with GPCR receptor proteins, the evolutionary ancestry of the members of this family can be traced back to the Archaea. |
GO component: | integral component of membrane (GO:0016021) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry HlyIII