The domain within your query sequence starts at position 733 and ends at position 853; the E-value for the Hydantoinase_B domain shown below is 2.3e-46.
LDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVH LGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQSRPVFYVAS
Hydantoinase_B |
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PFAM accession number: | PF02538 |
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Interpro abstract (IPR003692): | An appreciable fraction of the sulphur present in mammals occurs in the form of glutathione. The synthesis of glutathione and its utilization take place by the reactions of the gamma-glutamyl cycle, which include those catalysed by gamma-glutamylcysteine and glutathione synthetases, gamma-glutamyl transpeptidase, cysteinylglycinase, gamma-glutamyl cyclotransferease, and 5-oxoprolinase [ (PUBMED:45011) ]. This domain is found in N-methylhydantoinase B, which converts hydantoin to N-carbamyl-amino acids, and in 5-oxoprolinase EC 3.5.2.9 which catalyses the formation of L-glutamate from 5-oxo-L-proline. These enzymes are part of the oxoprolinase family. |
GO function: | catalytic activity (GO:0003824) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Hydantoinase_B