The domain within your query sequence starts at position 311 and ends at position 351; the E-value for the Involucrin2 domain shown below is 4.6e-14.



PFAM accession number:PF06994
Interpro abstract (IPR009733):

This domain represents a conserved region approximately 60 residues long, multiple copies of which are found within eukaryotic involucrin, and which is rich in glutamine and glutamic acid residues. Involucrin forms part of the insoluble cornified cell envelope (a specialised protective barrier) of stratified squamous epithelia [ (PUBMED:12210515) ].

GO process:keratinocyte differentiation (GO:0030216)
GO component:cornified envelope (GO:0001533)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Involucrin2