The domain within your query sequence starts at position 344 and ends at position 499; the E-value for the LAP2alpha domain shown below is 2.5e-11.
EGPIIDVLEHSKRGNTASPLDSTSKEMEVMGCRFYHAASIAARAASYMAYMTQYQRKLWE DMEDLVHDPEFDRGKARCIISDGMDAGLWQLCTTRDIMDSVVRVMAMAVDYRRQAWLRLT SLTKKTQEKILHLPFDGTSLFGQDVNAIVAEDNSIK
LAP2alpha |
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PFAM accession number: | PF11560 |
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Interpro abstract (IPR021623): | LAPs are components of the nuclear lamina which supports the nuclear envelope. LAP2alpha is a non-membrane-associated member of the LAP family which is unique. This entry represents the C-terminal domain of LAP2alpha which consists of residues 459-693 and constitutes a dimeric structure with an antiparallel coiled coil. LAP2alpha is involved in cell-cycle regulation and chromatin organisation and preferentially binds to lamin A/C [ (PUBMED:17562312) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry LAP2alpha