The domain within your query sequence starts at position 27 and ends at position 378; the E-value for the LAX domain shown below is 2.4e-172.
LQGEKGQIIFPGFVVLLTIILVIIAACILWSWKKQKKRPVPYFQVAPSLTLPPPRHRAKN IYDFLPRQQTELGRHQLSGFSTESLLSRASDSPEPEAPQANGSLQMHRVSVHTVEYSVNI YDNGTVPQMCRHLASSTHHVCVRTSRSNPSISSKESNDYVNIPTVEDTCETLTRIESTPE NHLGLPSALRLEFAEGGHAGCGNATDHDGFWAPGPKCSDSLSDGDDLSQTSNDYVNMTGL DLENIQENRPRGAFQCCRDYENVPWVDTNESQLPTLEEVASSTVDHREPVWRTLSSVYHM AFQPSAQSEDSAMVHREEQSSEDSSDYETVLVAELEGRDWKQGPGTQHPSDE
LAX |
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PFAM accession number: | PF15681 |
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Interpro abstract (IPR031393): | LAX is a family of proteins is found in chordates. LAX is membrane-associated and expressed in B cells, T cells, and other lymphoid-specific cell types. It down-regulates antigen-receptor signalling in T cells by inhibiting TCR-mediated p38 MAPK activation [ (PUBMED:12359715) (PUBMED:15843560) ]. |
GO process: | immune response (GO:0006955), regulation of lymphocyte activation (GO:0051249) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry LAX