The domain within your query sequence starts at position 200 and ends at position 273; the E-value for the Ldh_1_C domain shown below is 5.7e-13.
VWSGVNVAGVSLKSLNPELGTDADKEQWKEVHKQVVD
Ldh_1_C |
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| PFAM accession number: | PF02866 |
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| Interpro abstract (IPR022383): | L-lactate dehydrogenases are metabolic enzymes which catalyse the conversion of L-lactate to pyruvate, the last step in anaerobic glycolysis [ (PUBMED:11276087) ]. L-lactate dehydrogenase is also found as a lens crystallin in bird and crocodile eyes. L-2-hydroxyisocaproate dehydrogenases are also members of the family. Malate dehydrogenases catalyse the interconversion of malate to oxaloacetate [ (PUBMED:8117664) ]. The enzyme participates in the citric acid cycle. This entry represents the C-terminal, and is thought to be an is an unusual alpha+beta fold. |
| GO process: | oxidation-reduction process (GO:0055114) |
| GO function: | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Ldh_1_C