SMART: Pfam domain LicD

The domain within your query sequence starts at position 334 and ends at position 374; the E-value for the LicD domain shown below is 1.5e-15.

EAAGVRYWLEGGSLLGAARHGDIIPWDYDVDLGIYLEDVGN

LicD

PFAM accession number:	PF04991
Interpro abstract (IPR007074):	The LicD family of proteins show high sequence similarity and are involved in phosphorylcholine metabolism. There is evidence to show that LicD2 mutants have a reduced ability to take up choline, have decreased ability to adhere to host cells and are less virulent [ (PUBMED:10200966) ]. These proteins are part of the nucleotidyltransferase superfamily [ (PUBMED:19833706) ]. Fukutin, which is a member of the LicD family, is a human protein which may be involved in the modification of glycan moieties of alpha-dystroglycan; defects in Fukutin are associated with congential muscular dystrophy [ (PUBMED:11445638) ].

PFAM accession number:

PF04991

Interpro abstract (IPR007074):

The LicD family of proteins show high sequence similarity and are involved in phosphorylcholine metabolism. There is evidence to show that LicD2 mutants have a reduced ability to take up choline, have decreased ability to adhere to host cells and are less virulent [ (PUBMED:10200966) ]. These proteins are part of the nucleotidyltransferase superfamily [ (PUBMED:19833706) ].

Fukutin, which is a member of the LicD family, is a human protein which may be involved in the modification of glycan moieties of alpha-dystroglycan; defects in Fukutin are associated with congential muscular dystrophy [ (PUBMED:11445638) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry LicD