The domain within your query sequence starts at position 257 and ends at position 511; the E-value for the MTBP_C domain shown below is 2.5e-129.

PELSPGKLQVLPFEKASECHYHGIEYCLDDQKALERDGGFSELQSRLIRYETQTTCTRDS
FPVPTVLSPLPSPAVLSEPQSVPEGEALQGELRTEVSGLKRRSKDPSCLYPQKRLTRSES
SDCLPSQASCNSNHHHHTGKPRKPQAERCVSGLPLPGREASKDTSKTSSGQKRAHESKSS
KQMKESRSQKHTRMLKEVVKDTLKRHHITEAHESFTACSQRLFDISKFYLKDLKTSRGLF
EEMKKTANNNVVQVI

MTBP_C

MTBP_C
PFAM accession number:PF14920
Interpro abstract (IPR029418):

This entry represents the C-terminal domain of the MDM2-binding protein (MTBP). MDM2 is an E3 ubiquitin-protein ligase that mediates ubiquitination of p53, leading to its degradation by the proteasome [ (PUBMED:14707283) ]. MTBP inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability, and this promotes MDM2-mediated ubiquitination of p53 and its subsequent degradation [ (PUBMED:15632057) ]. Mouse MTBP also inhibits cancer cell migration by interacting with alpha-actinin-4 (ACTN4) [ (PUBMED:22370640) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry MTBP_C