The domain within your query sequence starts at position 25 and ends at position 202; the E-value for the Maf1 domain shown below is 4.6e-67.



PFAM accession number:PF09174
Interpro abstract (IPR015257):

Maf1 is a negative regulator of RNA polymerase III [ (PUBMED:11438659) (PUBMED:16762835) ]. It inhibits the de novo assembly of TFIIIB onto DNA [ (PUBMED:17785443) ]. Maf1 represses Pol III in response to DNA damage, oxidative stress, growth to stationary phase, treatment with rapamycin or chlorpromazine, and blocking of the secretory pathway [ (PUBMED:15196897) ]. It targets the initiation factor TFIIIB [ (PUBMED:12504022) ]. Its structure has been solved [ (PUBMED:20887893) ].

GO process:negative regulation of transcription by RNA polymerase III (GO:0016480)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Maf1