The domain within your query sequence starts at position 166 and ends at position 995; the E-value for the Meckelin domain shown below is < 1e-12.

ANALGTRCVRCEPTFVNTSRSCSCSEPHTLTGGLCFSNTGNFHQRVISTARYGELGMSLN
SEWFAKYLQATAAACWTHANLTSCQALGNMCVMNMNSYDSTTLDACRLFHYIFESTAGLI
SVHSVPFWRQNLPWLFYGDQPGLAPQVLSTTPLPTNFSFKGQNQLKFVAASYDIRGNFIK
WQPLEGGVLQLCPDTERRLDAAYAFGTTYQQNCEISLSKLLVDFSSPVFYDVYLEYTDEE
QHRYLWPIPVLNLNLQHNKLFVNQDSSSSKWLLTRRIFLVDAVSGRENDLGNQPRVIRVA
TQISLSIRLVPNTKNGNIYTPLLTIAYSDIDIKNAHSQSAKISFSVKYEMNQGDASVHTD
IALGVLGGLAVLSSLLKTAGWKRRIGSPMIDLQTVMKFLLYYAGDLANVFFIITVGTGLY
WLIFFKAQKSVSVLLPMPVQEERFVTYVGCAFAMKALQFLHKFISQISIDIFFIDWERPK
GKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRKINPLFQVLTTLFFLEVVGFK
NLALMDSSSSLSRNPSDYTAPYSRILRYAVATAIWLVIGIIQVVFFAAFYERFIEDKIRQ
FVDLCSMSNVSVFLLSHRCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLVPN
TDGQTFQIAVSSQMRQHYDRIHETLTRRNGPARLLSSSGSTFEQSIKAYHAMNKFLGSFI
DHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFYNDEGHSFSSVLYYGNEATLLIFDLL
FFCVVDLACQDFVLASFLTYLQQEIFRFIRNTVGQKNLATKTLVDERFLI

Meckelin

Meckelin
PFAM accession number:PF09773
Interpro abstract (IPR019170):

Meckelin (also known as MKS3) is part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition [ (PUBMED:17185389) ]. It is involved in centrosome migration to the apical cell surface during early ciliogenesis. It is required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication [ (PUBMED:19515853) ]. It is essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (sftpc) [ (PUBMED:21725307) ].

Defects in the meckelin gene leads to a broad spectrum of disorders, collectively termed ciliopathies. The ciliopathy range of diseases includes Meckel-Gruber syndrome, Bardet-Biedl syndrome, Joubert syndrome, and nephronophtisis among others [ (PUBMED:17185389) (PUBMED:171609) (PUBMED:19058225) (PUBMED:19508969) ].

GO process:cilium assembly (GO:0060271)
GO component:MKS complex (GO:0036038)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Meckelin