The domain within your query sequence starts at position 31 and ends at position 154; the E-value for the NIF3 domain shown below is 2e-40.



PFAM accession number:PF01784
Interpro abstract (IPR002678):

In Helicobacter pylori, GTP cyclohydrolase 1 type 2 converts GTP to dihydroneopterin triphosphate [ (PUBMED:23825549) ].

Nif3 interacts with the yeast transcriptional coactivator Ngg1p which is part of the ADA complex, the exact function of this interaction is unknown [ (PUBMED:11124544) (PUBMED:8663102) ].

This family includes GTP cyclohydrolase 1 type 2 proteins from bacteria and Nif3 from budding yeasts.

The structure of the Methanocaldococcus jannaschii MJ0927 Nif3 protein has been determined [ (PUBMED:23295494) (PUBMED:25243119) ]. It binds to both single-stranded and double-stranded DNA [ (PUBMED:25243119) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry NIF3