SMART: Pfam domain NRIP1_repr

The domain within your query sequence starts at position 27 and ends at position 331; the E-value for the NRIP1_repr_1 domain shown below is 5.4e-141.

HQAAGGSGTAINKKSAGHKEEDQNFNLSGSAFPSCQSNGPTVSTQTYQGSGMLHLKKARL
LQSSEDWNAAKRKRLSDSIVNLNVKKEALLAGMVDSVPKGKQDSTLLASLLQSFSSRLQT
VALSQQIRQSLKEQGYALSHESLKVEKDLRCYGVASSHLKTLLKKSKTKDQKSGPTLPDV
TPNLIRDSFVESSHPAVGQSGTKVMSEPLSCAARLQAVASMVEKRASPAASPKPSVACSQ
LALLLSSEAHLQQYSREHALKTQNAHQVASERLAAMARLQENGQKDVGSSQLSKGVSGHL
NGQAR

NRIP1_repr_1

PFAM accession number:	PF15687
Interpro abstract (IPR031405):	This domain is the first (N-terminal) repression domain of nuclear receptor-interacting protein 1 [ (PUBMED:14736873) (PUBMED:15060175) ]. Nuclear receptor-interacting protein 1 (also known as nuclear factor RIP140) modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1 [ (PUBMED:7641693) ]. It also modulates transcriptional repression by nuclear hormone receptors [ (PUBMED:10364267) ] and clock gene expression [ (PUBMED:21628546) ]. It consists of four distinct autonomous repression domains [ (PUBMED:14736873) ].

PFAM accession number:

PF15687

Interpro abstract (IPR031405):

This domain is the first (N-terminal) repression domain of nuclear receptor-interacting protein 1 [ (PUBMED:14736873) (PUBMED:15060175) ].

Nuclear receptor-interacting protein 1 (also known as nuclear factor RIP140) modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1 [ (PUBMED:7641693) ]. It also modulates transcriptional repression by nuclear hormone receptors [ (PUBMED:10364267) ] and clock gene expression [ (PUBMED:21628546) ]. It consists of four distinct autonomous repression domains [ (PUBMED:14736873) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry NRIP1_repr_1