The domain within your query sequence starts at position 754 and ends at position 841; the E-value for the NRIP1_repr_3 domain shown below is 8.4e-45.
VKIKSEPCDDFQTHNTNLPLNHDAKSAPFLGVTPAIHRSTAALPVSEDFKSEPASPQDFS FSKNGLLSRLLRQNQESYPADEQDKSHR
NRIP1_repr_3 |
---|
PFAM accession number: | PF15689 |
---|---|
Interpro abstract (IPR031407): | This domain is the third repression domain of nuclear receptor-interacting protein 1 [ (PUBMED:14736873) (PUBMED:15060175) ]. Nuclear receptor-interacting protein 1 (also known as nuclear factor RIP140) modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1 [ (PUBMED:7641693) ]. It also modulates transcriptional repression by nuclear hormone receptors [ (PUBMED:10364267) ] and clock gene expression [ (PUBMED:21628546) ]. It consists of four distinct autonomous repression domains [ (PUBMED:14736873) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry NRIP1_repr_3