SMART: Pfam domain NRIP1_repr

The domain within your query sequence starts at position 849 and ends at position 1161; the E-value for the NRIP1_repr_4 domain shown below is 1.7e-157.

ESKNICMVPKKRKLYTEPLENPFKKMKNTAVDTANHHSGPEVLYGSLLHQEELKFSRNEL
DYKYPAGHSSASDGDHRSWARESKSFNVLKQLLLSENCVRDLSPHRSDSVPDTKKKGHKN
NAPGSKPEFGISSLNGLMYSSPQPGSCVTDHRTFSYPGMVKTPLSPPFPEHLGCVGSRPE
PGLLNGCSVPGEKGPIKWVIADMDKNEYEKDSPRLTKTNPILYYMLQKGGGNSVTTQETQ
DKDIWREPASAESLSQVTVKEELLPAAETKASFFNLRSPYNSHMGNNASRPHSTNGEVYG
LLGNALTIKKESE

NRIP1_repr_4

PFAM accession number:	PF15690
Interpro abstract (IPR031408):	This domain is the fourth (C-terminal) repression domain of nuclear receptor-interacting protein 1 [ (PUBMED:14736873) (PUBMED:15060175) ]. Nuclear receptor-interacting protein 1 (also known as nuclear factor RIP140) modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1 [ (PUBMED:7641693) ]. It also modulates transcriptional repression by nuclear hormone receptors [ (PUBMED:10364267) ] and clock gene expression [ (PUBMED:21628546) ]. It consists of four distinct autonomous repression domains [ (PUBMED:14736873) ].

PFAM accession number:

PF15690

Interpro abstract (IPR031408):

This domain is the fourth (C-terminal) repression domain of nuclear receptor-interacting protein 1 [ (PUBMED:14736873) (PUBMED:15060175) ].

Nuclear receptor-interacting protein 1 (also known as nuclear factor RIP140) modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1 [ (PUBMED:7641693) ]. It also modulates transcriptional repression by nuclear hormone receptors [ (PUBMED:10364267) ] and clock gene expression [ (PUBMED:21628546) ]. It consists of four distinct autonomous repression domains [ (PUBMED:14736873) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry NRIP1_repr_4