The domain within your query sequence starts at position 126 and ends at position 268; the E-value for the PITH domain shown below is 1.8e-44.



PFAM accession number:PF06201
Interpro abstract (IPR010400):

This entry represents the PITH domain (derived from Proteasome-Interacting THioredoxin). The protein Txnl1, which is a probable component of the 32kDa 26S proteasome, uses its C-terminal PITH domain to associate specifically with the 26S proteasome [ (PUBMED:19349277) ].

The PITH domain is dominated by a jelly roll beta-sandwich structure. The beta-sandwich is formed by face-to-face packing of two anti-parallel beta-sheets. Another two-stranded beta-sheet seals off one end of the beta-barrel [ (PUBMED:15741346) (PUBMED:20455272) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry PITH