SMART: Pfam domain Q

The domain within your query sequence starts at position 53 and ends at position 338; the E-value for the Q_salvage domain shown below is 9.7e-122.

LNPRGADEAALGWVFLVDSLNFSFWAEREDSKCAVRYGGTPYTGYWALCAAVNRALDQGI
PITSASYYATVSLEQVRDIFRSDTAVPMPLMEERHRILNETGKILLEKFGGSFLNCVQKS
GRSAQKLMQLIVENFPSYRDEAEFEGKRIAFYKRAQILVADTWSVLEGKGDGCFEDISSI
TMFADYRLPQILVYLGALKYSDELLKKLLKGEMLLNGDKQEVEIRGCSIWCVELIRDRLL
ELLEKGENSPVEINSVLLDYHLWDYAREHREDMKGVPFHRTRCIYY

Q_salvage

PFAM accession number:	PF10343
Interpro abstract (IPR019438):	Queuosine salvage proteins occur in most Eukarya as well as in a few bacteria possible via horizontal gene-transfer. Queuosine (Q) is a chemical modification found at the wobble position of tRNAs that have GUN anticodons. Most bacteria synthesize queuosine de novo, whereas eukaryotes rely solely on salvaging this essential component from the environment or the gut flora. The exact enzymatic function of the domain has yet to be determined, but structural similarity with DNA glycosidases suggests a ribonucleoside hydrolase role [ (PUBMED:24911101) ].

PFAM accession number:

PF10343

Interpro abstract (IPR019438):

Queuosine salvage proteins occur in most Eukarya as well as in a few bacteria possible via horizontal gene-transfer. Queuosine (Q) is a chemical modification found at the wobble position of tRNAs that have GUN anticodons. Most bacteria synthesize queuosine de novo, whereas eukaryotes rely solely on salvaging this essential component from the environment or the gut flora. The exact enzymatic function of the domain has yet to be determined, but structural similarity with DNA glycosidases suggests a ribonucleoside hydrolase role [ (PUBMED:24911101) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Q_salvage