The domain within your query sequence starts at position 106 and ends at position 176; the E-value for the RFX1_trans_act domain shown below is 9.6e-9.



PFAM accession number:PF04589
Interpro abstract (IPR007668):

The RFX family is a family of winged-helix DNA-binding proteins. RFX1 is a regulatory factor essential for expression of MHC class II genes. This region is found N-terminal to the RFX DNA-binding region ( IPR003150 ) in some mammalian RFX proteins, and is thought to activate transcription when associated with DNA. Deletion analysis has identified the region 233-351 in human RFX1 ( P22670 ) as being required for maximal activation [ (PUBMED:9278482) ].

GO process:regulation of transcription, DNA-templated (GO:0006355)
GO component:nucleus (GO:0005634)
GO function:DNA binding (GO:0003677)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry RFX1_trans_act