The domain within your query sequence starts at position 1 and ends at position 253; the E-value for the RITA domain shown below is 2.5e-105.
MKALHLQHRSPTSYRVKARASYVDETLFGSPARTRPAQPDFDPPWVQNCNRSRGVGPGPP KGSLAKRDCESPSSRGSTPNLTPRKKNKYRLIGHAPSYCDESLFGTSKEGSRMAVGDAAK LRTLFWTPPATPRGSHTPCPRETPLRAIHPAGPSRTEPRVTAGSQMSSQDGLCVPCSLGQ RRSHSLTHLTVPSTGHPASSAPQTNGPWSPRPNTSGATVQSPLVTSKACSGRVSGPAPPR RGACPPKPKPPWK
RITA |
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PFAM accession number: | PF17066 |
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Interpro abstract (IPR031418): | RITA (RBPJ-interacting and tubulin-associated protein) is a highly conserved protein that binds to tubulin and shuttles between the cytoplasm and nucleus. It is responsible for export of RBP-J/CBF-1 from the nucleus, which modulates Notch-mediated transcription [ (PUBMED:21102556) ]. |
GO process: | Notch signaling pathway (GO:0007219), nuclear export (GO:0051168) |
GO function: | tubulin binding (GO:0015631) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry RITA