The domain within your query sequence starts at position 670 and ends at position 1031; the E-value for the RNA_pol_Rpb2_6 domain shown below is 9.7e-118.

IANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQNRSDNKLYRLQTPQSPLVRPCMYDF
YDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFIDLSEKFKQGE
DNLVFGVKPGDPRVMQKLDDDGLPFIGAKLEYGDPYYSYLNLNTGEGFVVYYKSKENCVV
DNIKVCSNDMGSGKFKCICITVRIPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGM
MPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAA
GYNFYGTERLYSGISGMELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDKVTNQPLGGR
NV

RNA_pol_Rpb2_6

• PFAM accession number: PF00562
• Interpro abstract (IPR007120):

  RNA polymerases ( EC 2.7.7.6 ) catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial and chloroplast polymerases). This domain represents the hybrid-binding domain and the wall domain [ (PUBMED:11313498) ]. The hybrid-binding domain binds the nascent RNA strand/template DNA strand in the Pol II transcription elongation complex. This domain contains the important structural motifs, switch 3 and the flap loop and binds an active site metal ion [ (PUBMED:11313498) ]. This domain is also involved in binding to Rpb1 and Rpb3 [ (PUBMED:11313498) ]. Many of the bacterial members contain large insertions within this domain, which are known as dispensable region 2 (DRII).

• GO process: transcription, DNA-templated (GO:0006351)
• GO function: DNA binding (GO:0003677), DNA-directed 5'-3' RNA polymerase activity (GO:0003899)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry RNA_pol_Rpb2_6