The domain within your query sequence starts at position 331 and ends at position 394; the E-value for the Rsm1 domain shown below is 4.6e-8.
ATVSPGSEQDTSPRSFFDPTSQHRDWCPWVNITLVKETKENGETEVDACTPAEPGWKAVL TILL
Rsm1 |
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PFAM accession number: | PF08600 |
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Interpro abstract (IPR013909): | This entry contains Nuclear-interacting partner of ALK (NIPA) and NIPA like proteins, as well as mRNA export factor Rsm1, all of which contain a C3HC-type zinc finger. The domain represented in this entry is found C-terminal to the zinc-finger like domain IPR012935 . Rsm1 is involved in mRNA export from the nucleus [ (PUBMED:15357289) ]. NIPA is an essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry [ (PUBMED:16009132) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Rsm1