The domain within your query sequence starts at position 1471 and ends at position 1721; the E-value for the SPAR_C domain shown below is 1.6e-96.
KQVDTNAKNVFGQPRLRASLRDLRSPRKNYKSTIEDDLKKLIVMDNLGPEQERDTGQSPQ KSLQRTLSDESLCSGRREPSFASPASLEPGLPSDVLFTSTCTFPSSTLPARRQHQHAHPP SGAPSTTPATGNGFPEKKSAISASELSLADGRDRPLRRLDPGMMPLPDTAAGLEWSSLVN AAKAYEVQRAVSLFSLNDPALSPEIPPAHSPVHSHLSLERGPQTPRATPTMSEESPLDLT GKVYQLEVMLK
SPAR_C |
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PFAM accession number: | PF11881 |
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Interpro abstract (IPR021818): | This domain is found in C-terminal of the signal-induced proliferation-associated 1-like (SIPA1L) proteins, including SIPA1L 1-3 from humans. SIPA1Ls shares protein sequence similarity with signal-induced proliferation-associated protein 1 (SIPA1), which is a GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 [ (PUBMED:9346962) (PUBMED:15310461) ]. In rats SIPA1L1 (also known as SPAR) has been identified as a Rap-specific GTPase-activating protein [ (PUBMED:11502259) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry SPAR_C