The domain within your query sequence starts at position 33 and ends at position 436; the E-value for the SPICE domain shown below is 1.4e-151.
NTVNDLTVHRATPEDLVRRHEMHKSKNRALVHWELQEKALKRKWKKQKPETSSLEKRKLS IMKEILSDQYLTQDVLEKSDHLMAAAKGLFADVPRKRTGFPNVTRAPDSSQSHTGINQDP VTQSILNESIIEPQALNEVDDAGEQSTAHSQSEDSENELPNSLSQHSNRSTERFLHQLKE ENSELINQLWTDIQQKIATQSQRTPPGSPSSELSAEDQKAALNATDAVKRIQAGPQPEEA AEPVDFSSSYLGQVLNTRKQKPLLAKVKRKQDMHAASKQKTNMLSSSTASADRPSSTGSS LDVLKHVIHEVEHEMEEYERCTGREVTGLQGGQGLTGFTLSLVSSLCRLVRYLKESEIQL RKEVETRQQLEQMLGDHRELIDALTAEILSLREENSTMQARLQQ
SPICE |
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PFAM accession number: | PF15678 |
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Interpro abstract (IPR031387): | SPICE1 localises to spindle microtubules in mitosis and to centrioles throughout the cell cycle. Deletion of SPICE1 compromises the architecture of spindles, the integrity of the spindle pole and the process of aligning chromosomes on the spindle (chromosome congression) [ (PUBMED:20736305) ]. SPICE1 interacts with CEP120 in centriole duplication and elongation [ (PUBMED:23810536) ]. |
GO process: | mitotic spindle assembly (GO:0090307) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry SPICE