The domain within your query sequence starts at position 33 and ends at position 253; the E-value for the Sec1 domain shown below is 1.2e-48.



PFAM accession number:PF00995
Interpro abstract (IPR001619):

Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [ (PUBMED:8769846) ]. They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion [ (PUBMED:10903948) ].

GO process:vesicle-mediated transport (GO:0016192), vesicle docking involved in exocytosis (GO:0006904)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Sec1