SMART: Pfam domain Shal-type

The domain within your query sequence starts at position 3 and ends at position 31; the E-value for the Shal-type domain shown below is 4.5e-16.

AGVAAWLPFARAAAIGWMPVASGPMPAPP

Shal-type

PFAM accession number:	PF11601
Interpro abstract (IPR021645):	This entry represents the N-terminal helical domain of the Shal-type voltage-gated potassium channels. This domain interact with Kv channel-interacting proteins to modulate cell surface expression and function of Kv4 channels. The interaction of the Shal-type protein Kv4.2 and the Kv interacting protein KChiP1 forms a structure which is like the structure between calmodulin and its target peptides when they interact. Interactions of an N-terminal alpha helix in Kv4.2 and a C-terminal alpha helix in KChIP1 are essential for the modulation of Kv4.2 by KChIPs [ (PUBMED:14980206) ].

PFAM accession number:

PF11601

Interpro abstract (IPR021645):

This entry represents the N-terminal helical domain of the Shal-type voltage-gated potassium channels. This domain interact with Kv channel-interacting proteins to modulate cell surface expression and function of Kv4 channels. The interaction of the Shal-type protein Kv4.2 and the Kv interacting protein KChiP1 forms a structure which is like the structure between calmodulin and its target peptides when they interact. Interactions of an N-terminal alpha helix in Kv4.2 and a C-terminal alpha helix in KChIP1 are essential for the modulation of Kv4.2 by KChIPs [ (PUBMED:14980206) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Shal-type