The domain within your query sequence starts at position 10 and ends at position 590; the E-value for the TH1 domain shown below is 5.6e-303.

MGEDYFGNASEWGEEADGGQHQEDDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKR
YFQAGGSPENVIQLLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFD
PRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEI
TSVSTACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVL
AQEEQGGSAVRRVAQEVQRFAQEKGHDASQITLALGTAASYPRACQALGAMLSRGALNPA
DITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGAKINQDHKHKYIHILAYAASVVE
TWKKNKRVSIGKDELKSTSKAIETVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVL
KWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVME
QLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSD
FVQLFLPILENDSIAGTIKAEGEHDPVTEFIAHCKSNFIVV

TH1

• PFAM accession number: PF04858
• Interpro abstract (IPR006942):

  TH1 is a highly conserved but uncharacterised metazoan protein. No homologue has been identified in Caenorhabditis elegans [ (PUBMED:11030415) ]. TH1 binds specifically to A-Raf kinase [ (PUBMED:11952167) ].

• GO process: negative regulation of transcription, DNA-templated (GO:0045892)
• GO component: nucleus (GO:0005634)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry TH1