The domain within your query sequence starts at position 44 and ends at position 336; the E-value for the TMEM173 domain shown below is 4.7e-125.

LKYLALHLASHELGLLLKNLCCLAEELCHVQSRYQGSYWKAVRACLGCPIHCMAMILLSS
YFYFLQNTADIYLSWMFGLLVLYKSLSMLLGLQSLTPAEVSAVCEEKKLNVAHGLAWSYY
IGYLRLILPGLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDNLSVVDPNIRFRDM
LPQQNIDRAGIKNRVYSNSVYEILENGQPAGVCILEYATPLQTLFAMSQDAKAGFSREDR
LEQAKLFCRTLEEILEDVPESRNNCRLIVYQEPTDGNSFSLSQEVLRHIRQEE

TMEM173

 TMEM173
PFAM accession number:PF15009
Interpro abstract (IPR029158):

Transmembrane protein 173, also known as stimulator of interferon genes protein (STING) or endoplasmic reticulum interferon stimulator (ERIS), is a transmembrane adaptor protein which is involved in innate immune signalling processes. It induces expression of type I interferons (IFN-alpha and IFN-beta) via the NF-kappa-B and IRF3, pathways in response to non-self cytosolic RNA and dsDNA [ (PUBMED:18724357) (PUBMED:19776740) (PUBMED:18818105) (PUBMED:19433799) ].

GO process:positive regulation of type I interferon production (GO:0032481), activation of innate immune response (GO:0002218)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry TMEM173