The domain within your query sequence starts at position 11 and ends at position 82; the E-value for the TORC_N domain shown below is 1.2e-20.



PFAM accession number:PF12884
Interpro abstract (IPR024783):

This entry represents the N-terminal domain of TORC proteins. TORC (transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-dependent transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerisation domain of CREB (cAMP Response Element-Binding) [ (PUBMED:14536081) ]. The proteins display a highly conserved predicted N-terminal coiled-coil domain and an invariant sequence matching a protein kinase A (PKA) phosphorylation consensus sequence (RKXS) [ (PUBMED:14506290) ]. The coiled-coil structure interacts with the bZIP domain of CREB [ (PUBMED:14536081) ]. This interaction may occur via ionic bonds because it is disrupted under high-salt conditions [ (PUBMED:17565599) ]. In addition to CREB-binding, the N-terminal domain plays a role in the tetramer formation of TORCs [ (PUBMED:14536081) ], but the physiological function of the multimeric complex has not been clarified yet.

GO process:protein homotetramerization (GO:0051289)
GO function:cAMP response element binding protein binding (GO:0008140)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry TORC_N