The domain within your query sequence starts at position 20 and ends at position 137; the E-value for the TSLP domain shown below is 1.1e-49.
YNFSNCNFTSITKIYCNIIFHDLTGDLKGAKFEQIEDCESKPACLLKIEYYTLNPIPGCP SLPDKTFARRTREALNDHCPGYPETERNDGTQEMAQEVQNICLNQTSQILRLWYSFMQ
TSLP |
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PFAM accession number: | PF15216 |
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Interpro abstract (IPR029189): | Thymic stromal lymphopoietin (TSLP) is a cytokine that functions mainly on myeloid cells; it induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells [ (PUBMED:11418668) ]. TSLP has proliferative effects on the myeloid cell line [ (PUBMED:11480573) ] and may initiate asthma or atopic dermatitis responses by directly activating mast cells [ (PUBMED:17242164) ]. |
GO function: | cytokine activity (GO:0005125) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry TSLP