The domain within your query sequence starts at position 22 and ends at position 375; the E-value for the Tfb2 domain shown below is 1.9e-137.
EFLGGLSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRMLFLEQPLPQAAVALWVKKEFS KAQEESTGLLSGLRIWHTQLLPGGLQGLILNPVFRQNLRIALLGGGKAWSDDTSQLGPDK HARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLSQAGLMKSTEPGEPPCITSAG FQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQLSFSTLGKDYSVEGMSDSLLN FLQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGTVHQPGFIVVETNYRLYAYTE SELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGITAQQIIHFLRTRAHP
Tfb2 |
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PFAM accession number: | PF03849 |
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Interpro abstract (IPR004598): | This entry represents the p52/Tfb2 subunit in the TFIIH complex, which is not only required for transcription but also plays a central role in DNA repair. The TFIIH multiprotein complex consists of a 7-subunit core (XPB, p62, p52, p44, p34, and TTDA) that is associated with a 3-subunit CDK-activating kinase module (MAT1, cyclin H and Cdk7) [ (PUBMED:21592869) (PUBMED:22308316) (PUBMED:22572993) ]. The p52 subunit interacts with subunit XPB, which is an ATP-dependent 3'-5' DNA helicase, and stimulates its ATPase activity [ (PUBMED:17466626) ]. |
GO process: | nucleotide-excision repair (GO:0006289) |
GO component: | transcription factor TFIIH core complex (GO:0000439) |
GO function: | ATPase activator activity (GO:0001671) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Tfb2