The domain within your query sequence starts at position 8 and ends at position 287; the E-value for the Tfb4 domain shown below is 2.1e-108.

LNLLVIIVDTNPIWWGKQALKESQFTLSKCMDAVMVLANSHLFMNRSNQLAVIASHIQES
RLLYPGKNGGLGDFFGDPGNALPDCNPSGSKDGKYELLTVANEVIAEEIKDLMTKSDIKG
QHTETLLAGSLAKALCYIHRVNKAVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQK
QNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPP
IHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSPICTTCE

Tfb4

Tfb4
PFAM accession number:PF03850
Interpro abstract (IPR004600):

This entry represents Tfb4/GTF2H3, a component of the transcription factor TFIIH core (includes XPB, p62, p52, p44, p34). TFIIH complex is involved in the nucleotide excision repair (NER) and polymerase II transcription [ (PUBMED:7961739) (PUBMED:8631896) (PUBMED:10506223) ].

GO process:nucleotide-excision repair (GO:0006289), regulation of transcription, DNA-templated (GO:0006355)
GO component:transcription factor TFIIH core complex (GO:0000439)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Tfb4