SMART: Pfam domain Tho2

The domain within your query sequence starts at position 873 and ends at position 1173; the E-value for the Tho2 domain shown below is 3.3e-109.

WDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKVQMKAIDDNQEMPPNKKKKEKERCT
ALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKSTKNETITKFLQLCIFPRCIFSAID
AVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIYTVASCTENEASRYGRFLCCMLETVTR
WHSDRATYEKECGNYPGFLTILRATGFDGGNKADQLDYENFRHVVHKWHYKLTKASVHCL
ETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVNKICQEEKEKRPDLYALAMGYSGQ
L

Tho2

PFAM accession number:	PF11262
Interpro abstract (IPR021418):	THO and TREX form a eukaryotic complex which functions in messenger ribonucleoprotein metabolism and plays a role in preventing the transcription-associated genetic instability [ (PUBMED:16581804) ],[ (PUBMED:17960421) ]. Tho2, along with four other subunits forms THO [ (PUBMED:17960421) ]. This entry represents a conserved domain found towards the C terminus of these proteins.

PFAM accession number:

PF11262

Interpro abstract (IPR021418):

THO and TREX form a eukaryotic complex which functions in messenger ribonucleoprotein metabolism and plays a role in preventing the transcription-associated genetic instability [ (PUBMED:16581804) ],[ (PUBMED:17960421) ]. Tho2, along with four other subunits forms THO [ (PUBMED:17960421) ].

This entry represents a conserved domain found towards the C terminus of these proteins.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Tho2