The domain within your query sequence starts at position 1208 and ends at position 1343; the E-value for the U5_2-snRNA_bdg domain shown below is 1.9e-73.



PFAM accession number:PF10597
Interpro abstract (IPR019581):

The essential spliceosomal protein Prp8 interacts with U5 and U6 snRNAs and with specific pre-mRNA sequences that participate in catalysis [ (PUBMED:16431982) ]. This close association with crucial RNA sequences, together with extensive genetic evidence, suggests that Prp8 could directly affect the function of the catalytic core, perhaps acting as a splicing cofactor [ (PUBMED:16431982) ].

GO function:U5 snRNA binding (GO:0030623)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry U5_2-snRNA_bdg