The domain within your query sequence starts at position 154 and ends at position 208; the E-value for the VEGF_C domain shown below is 9.5e-35.



PFAM accession number:PF14554
Interpro abstract (IPR027928):

This short domain is found at the C terminus of vascular endothelial growth factor (VEGF). It has been shown to have heparin binding activity [ (PUBMED:12061718) ].

Proteins containing this domain include VEGF-A, which is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth [ (PUBMED:7556923) ]. VEGF-A also promotes a wide range of neuronal functions, including neurogenesis, neuronal migration, neuronal survival and axon guidance [ (PUBMED:22434866) ].

GO function:heparin binding (GO:0008201)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry VEGF_C