SMART: Pfam domain WASH-7

The domain within your query sequence starts at position 966 and ends at position 1135; the E-value for the WASH-7_C domain shown below is 9.1e-76.

TLRAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFV
EHSISCKEKLNKKNKLGAAFTDDGFAMGVAYTLKLLDQYQEFDSLHWFQSVREKYIKEIR
AVAKQQNVQSTSQDEKLLQTMNLTQKRLEVYLQEFELLYFSLSSARIFFR

WASH-7_C

PFAM accession number:	PF14746
Interpro abstract (IPR028283):	This entry represents the C-terminal region of WASH complex subunit 7 (WASH7), also known as subunit 4 or KIAA1033 [ (PUBMED:19922875) ]. The WASH complex is present at the surface of endosomes and recruits and activates the Arp2/3 complex to induce mediated actin nucleation. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting [ (PUBMED:20888769) ]. This C-terminal domain is predicted to include a transmembrane region.

PFAM accession number:

PF14746

Interpro abstract (IPR028283):

This entry represents the C-terminal region of WASH complex subunit 7 (WASH7), also known as subunit 4 or KIAA1033 [ (PUBMED:19922875) ]. The WASH complex is present at the surface of endosomes and recruits and activates the Arp2/3 complex to induce mediated actin nucleation. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting [ (PUBMED:20888769) ]. This C-terminal domain is predicted to include a transmembrane region.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry WASH-7_C