SMART: Pfam domain dNK

The domain within your query sequence starts at position 24 and ends at position 258; the E-value for the dNK domain shown below is 2.5e-79.

ISIEGNIAAGKSTFVNILKQASEDWEVVPEPVARWCNVQSTQEEFEELTTSQKSGGNVLQ
MMYEKPERWSFTFQSYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYE
SDCMNETEWTIYQDWHDWMNSQFGQSLELDGIIYLRATPEKCLNRIYLRGRNEEQGIPLE
YLEKLHYKHESWLLHRTLKTSFDYLQEVPVLTLDVNEDFKDKHESLVEKVKEFLS

dNK

PFAM accession number:	PF01712
Interpro abstract (IPR031314):	This entry represents a domain found in various deoxynucleoside kinases including cytidine ( EC 2.7.1.74 ), guanosine ( EC 2.7.1.113 ), adenosine ( EC 2.7.1.76 ) and thymidine kinase ( EC 2.7.1.21 ), which also phosphorylates deoxyuridine and deoxycytosine. These enzymes catalyse the production of deoxynucleotide 5'-monophosphate from a deoxynucleoside, using ATP and yielding ADP in the process. Proteins containing this domain also include the subunit 10 (also known as CI-42kD) of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). It is an accessory subunit that is believed not to be involved in catalysis [ (PUBMED:9878551) ].

PFAM accession number:

PF01712

Interpro abstract (IPR031314):

This entry represents a domain found in various deoxynucleoside kinases including cytidine ( EC 2.7.1.74 ), guanosine ( EC 2.7.1.113 ), adenosine ( EC 2.7.1.76 ) and thymidine kinase ( EC 2.7.1.21 ), which also phosphorylates deoxyuridine and deoxycytosine. These enzymes catalyse the production of deoxynucleotide 5'-monophosphate from a deoxynucleoside, using ATP and yielding ADP in the process.

Proteins containing this domain also include the subunit 10 (also known as CI-42kD) of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). It is an accessory subunit that is believed not to be involved in catalysis [ (PUBMED:9878551) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry dNK