The domain within your query sequence starts at position 4 and ends at position 521; the E-value for the eIF-3_zeta domain shown below is 6.3e-220.

FMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQF
GGGSQYAYFHEEDETSFQLVDTARTQKTAYQRNRMRFAQRNLRRDKDRRNMVQFNLQTLP
KSAKQKERERIRLQKKFQKQFGVRQKWDQKSQKPRDSSVEVRSDWEVKEEMDFPQLMKMR
YLEVSEPQDIECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQG
NVFATDAILATLMSCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEG
NSFNSPRNLAMEATYINHNFSQQCLRMGRERYNFPNPNPFVEDDMDKNEIASVAYRYRRW
KLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIAT
ELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLS
VENAWGILRCVIDICMKLEEGKYLILKDPNKQVIRVYS

eIF-3_zeta

eIF-3_zeta
PFAM accession number:PF05091
Interpro abstract (IPR007783):

Eukaryotic translation initiation factor 3 subunit D (eIF3d) is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome [ (PUBMED:8995409) (PUBMED:15904532) ]. The gene coding for the protein has been implicated in cancer in mammals [ (PUBMED:11733359) ].

GO component:cytoplasm (GO:0005737), eukaryotic translation initiation factor 3 complex (GO:0005852)
GO function:translation initiation factor activity (GO:0003743)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry eIF-3_zeta