The domain within your query sequence starts at position 214 and ends at position 666; the E-value for the mit_SMPDase domain shown below is 1.3e-265.

KESFTPTEEHVLVVRLLLKHLHAFANSLKPDQASPSAHSHATSPLEEFKRAAVPRFVQQK
LYVFLQHCFGHWPLDATFRAVLEMWLSYLQPWRYAPEKQAQGSDPQPRCVSEKWAPFIQE
NLLMYTKLFVSFLNRALRTDLVSPKNALMVFRVAKVFAQPNLAEMIQKGEQLFLEPELII
PHRQHRLFTVTTSFLSPWPPVVTDASFKVKSHVYSLEGQDCKYTPMFGPEIRTLVLRLAQ
LITQAKQTAKSISDQYVESPTGRSFLSWLTFGLTDTNSCYPANDLDEIGQDSIRKTDEYL
EKALEYLRQIFRLSEAQLAQLTLALGSARDENGKQQLPDCIVGEEGLILTPLGRYQIING
LRRFEIEYQGDLELQPIRSYEITSLVRALFRLSSAINRRFAGQMAALCSRNDFLGSFCRY
HLTEPALSNRHLLSPVGRRQVTNPARGPRLSLR

mit_SMPDase

• PFAM accession number: PF14724
• Interpro abstract (IPR024129):

  Sphingomyelin phosphodiesterase 4 (also known as neutral sphingomyelinase 3) catalyses the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide [ (PUBMED:16517606) ].

• GO function: sphingomyelin phosphodiesterase D activity (GO:0050290)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry mit_SMPDase